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ChondroFiller® at the Liquid Cartilage

Injectable, Structural Regenerative Implant for Cartilage Care

Protect • Repair • Regenerate

Don’t Let Cartilage Damage Limit Your Life

Cartilage injuries can turn simple movement into a challenge. Without timely treatment, damage may progress and increase the risk of arthritis or future joint replacement.

At Liquid Cartilage, our goal isjoint preservation and regeneration—not replacement. WithChondroFiller®, we deliver advanced, evidence-led care on Harley Street.

Patient-friendly joint preservation care at Liquid Cartilage
“Repair first—keep the joint if we can.”
– Prof. Paul Lee

Why Healthy Cartilage Matters

Cartilage provides the smooth, low-friction surface that lets your joints move comfortably. It doesn’t readily self-repair, but with the right scaffold and biological cues,regeneration is possible.

Act early to preserve more of what you have.

ChondroFiller liquid scaffold visual

What Is ChondroFiller®?

ChondroFiller® is an acellular,biologic collagen scaffold delivered in liquid form. Once placed, itgels within minutes, filling the defect and providing a framework that invites your cells to rebuild cartilage.

Think of it like “epoxy” for cartilage—without the plastic.

  • Shields the damaged zone from further wear
  • Attracts native cells into a 3D scaffold
  • Supports hyaline-like regeneration (not just fibrous scar)

One treatment. One step. A chance to keep your joint for the long term.

The Evidence

Supported by a decade+ of publications and international clinical use.
Global use
>19,000
cases, no serious complications reported
Knee
+30
IKDC at 12–36 months
Hip
+33
Harris Hip Score; pain down by 6
Hand
½
pain halved; grip restored; MRI shows wider space
MRI
70–87
MOCART: consistent, high-quality repair
ChondroFiller treatment illustration 1
ChondroFiller treatment illustration 2

How Does It Compare?

ChondroFiller® sits in a different class—structural regenerative implant.

TreatmentAnalogyWhat it DoesLimitation
HA (Hyaluronic Acid)WD-40Improves lubrication for short-term comfortTemporary; does not regenerate tissue
Arthrosamid®SiliconeActs on the synovium to reduce pain signallingNot regenerative; literature notes complication rates up to 30%
ChondroFiller®Epoxy resinFills defects, stabilises, and promotes true cartilage repairMost robust injectable option for structural repair

Treatment Options at Liquid Cartilage

ChondroFiller®: our structural, regenerative approach to focal cartilage defects.

Ultrasound-Guided Precision Injections
£2,100–£2,800

Small joints: thumb, fingers, elbow, AC joint, toes, TMJ…

  • No incisions; minimal downtime
  • 1 ml of ChondroFiller
  • In-clinic procedure

From £2,100

Large joints: knee, hip, shoulder, ankle

  • In-clinic procedure
  • 2.3 ml of ChondroFiller
  • No incisions; minimal downtime

From £2,800

Keyhole Surgery (Large Joints)
£6,500–£9,500

Best for knee, hip, shoulder

  • Arthroscopic debridement
  • Direct ChondroFiller placement under vision
  • Ideal for larger/complex defects
  • ACIC (autologous collagen-induced chondrogenesis)
  • AMIC (autologous matrix-induced chondrogenesis)

From £6,500 (knee), £9,500 (hip/shoulder)

Liquid Cartilage™ (Exclusive)
£3,800–£9,500

Our proprietary MSC Co-Delivery Technique

  • Combines ChondroFiller® with MSC (medicinal signalling cells)from marrow, fat, or PRF
  • Inspired by ACI / MACI principles—delivered ina single procedure
  • Designed for larger or more complex defects
  • Best-in-class solution for cartilage loss
  • ACIC with cells
  • AMIC with cells
Injection: from £3,800 – Liquid Cartilage™
Keyhole: from £9,500 – Liquid Cartilage™

Your Journey with Us

Introductory offer: your consultation fee is credited toward treatment if you proceed.

Step 1

Discovery call

Discovery Call

Quick, no-obligation chat

Step 2

Consultation and MRI

Consultation + MRI

Comprehensive assessment with Prof. Paul Lee

Step 3

Tailored plan

Treatment Plan

Injection, Keyhole, or Liquid Cartilage™

Step 4

One-day procedure

One-Day Procedure

Precise and minimally invasive

Step 5

Rehab and follow up

Specialist Rehab & Follow-Up

Why Liquid Cartilage?

  • Prof. Paul Lee — Consultant Orthopaedic Surgeon & Honorary Professor of Sports Medicine; international leader in cartilage regeneration
  • Harley Street facilities withmotion capture and AI-supported diagnostics
  • Recognised as the UK ICRS Teaching Centre of Excellence
  • Regeneration-first philosophy: preserve joints whenever possible
Book a Discovery Call
Clinic environment
Patient recovering with guidance

Take the Next Step

Cartilage damage won’t reverse on its own—yet with the right plan it can beprotected, repaired, and regenerated.

At Liquid Cartilage, you access world-leading science and a joint-preservation vision on Harley Street.

  • Start with a Discovery Call.
  • Or book your Consultation with Prof. Lee today.

(Consultation fee credited towards treatment if you proceed.)

Verified by DoctifyVerified by Doctify

Frequently Asked Questions

Everything you want to know about ChondroFiller® at Liquid Cartilage.

What is ChondroFiller® and how does it support natural repair?

ChondroFiller® is an acellular collagen gel that fills cartilage defects and forms a scaffold for your own cells to regenerate healthy tissue. Unlike temporary injections, it supports hyaline-like restorationfor smoother motion and protection long-term.

How does it compare with other injections or joint replacement?

HA or Arthrosamid® may give short-term pain relief, while ChondroFiller® aims to rebuild cartilage. Compared with replacement, it preserves your natural joint and avoids prosthesis risks. Our approach is regenerate-first.

What outcomes have been reported?

Studies show +30 IKDC in knees,+33 Harris Hip Score in hips, and improved ankle metrics. MRI (MOCART) typically reads 70–87. Globally,>19,000 cases support safety and function.

Who is a good candidate?

Best for focal defects up to 6 cm² in knees, hips, ankles, or small joints. Active younger patients often benefit, but older patients may qualify if surrounding cartilage is stable.

What is the procedure and recovery like?

Delivered via precise injection orkeyhole surgery. The gel sets in minutes. Expectpartial weight-bearing ~6 weeks, steady return to cycling/swimming, and most sports around~12 months alongside specialist rehab.

Why choose us?

Harley Street location; UK ICRS Centre of Excellence. Led byProf. Paul Lee, with advanced options likeLiquid Cartilage™ (ChondroFiller® + cells) to prioritise preservation.

Download our Leaflet

Discover what makes ChondroFiller® unique at Liquid Cartilage.

Poster for London Cartilage Clinic featuring Professor Paul Lee, Consultant Orthopaedic Surgeon and Medical Engineer, highlighting Injectable Cartilage Regeneration with ChondroFiller®. The image explains that ChondroFiller® is a CE-marked type-I collagen gel injected directly into cartilage defects, delivered arthroscopically or fluoroscopically, and acts as a scaffold for natural cartilage regeneration. It describes clinical evidence showing improvement in knee, hip, ankle, and thumb joint conditions, and a rehabilitation pathway involving 48-hour protection, phased partial loading over 2–4 weeks, and AI-guided motion analysis for return to sport. Professor Lee is noted as Founder and Medical Director of London Cartilage Clinic on Harley Street, an international authority in regenerative surgery.Professor Paul Lee — London Cartilage Clinic expert in injectable cartilage regeneration. Promotional poster highlighting cartilage repair with ChondroFiller®: minimally invasive collagen gel injection for natural cartilage healing, faster recovery, and proven results. Suitable for knee, hip, ankle, and thumb cartilage injuries. Professor Paul Lee is an orthopaedic surgeon and PhD in Medical Engineering with 20+ years of experience in cartilage preservation. Located on Harley Street, the clinic offers AI-assisted motion tracking and world-class regenerative treatments. Private patients welcome, no GP referral required.

Latest Blog

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ChondroFiller: Revolutionising Cartilage Healing with a Minimally Invasive, Cell-Free Approach
17 Nov 2025

ChondroFiller: Revolutionising Cartilage Healing with a Minimally Invasive, Cell-Free Approach

ChondroFiller presents a novel, minimally invasive treatment for cartilage injuries, using a cell-free type I collagen gel to promote natural repair in damaged joints. Unlike traditional multi-step surgeries, this one-step arthroscopic procedure delivers the gel precisely via malleable needles, reducing recovery time and patient discomfort. Expert assessment by MSK Doctors ensures personalized care, optimizing outcomes for those suffering from full-thickness chondral defects. This innovative approach offers hope for improved joint function and faster healing, marking a significant advancement in orthopedic cartilage repair.

ChondroFiller versus Stem Cell Therapy: Which Is Simpler and More Effective for Persistent Ankle Pain after Sprains?
14 Nov 2025

ChondroFiller versus Stem Cell Therapy: Which Is Simpler and More Effective for Persistent Ankle Pain after Sprains?

Persistent ankle pain after sprains often stems from cartilage damage. Innovative treatments like ChondroFiller and stem cell therapy offer promising repair options. ChondroFiller is a simpler, one-step, minimally invasive procedure using a cell-free collagen matrix that supports natural cartilage healing without cell extraction. In contrast, stem cell therapy involves harvesting, processing, and injecting cells in multiple steps, making it more complex and time-consuming. Both methods improve joint function and reduce pain, but ChondroFiller typically allows quicker recovery with fewer hospital visits. Consulting experienced professionals ensures personalized care and optimal outcomes. Understanding these differences helps patients make informed decisions tailored to their lifestyle and needs.

Is Persistent Ankle Pain After Sprains Linked to Talus Cartilage Damage? Exploring ChondroFiller as a Modern Solution
12 Nov 2025

Is Persistent Ankle Pain After Sprains Linked to Talus Cartilage Damage? Exploring ChondroFiller as a Modern Solution

Persistent ankle pain after a sprain can result from unnoticed damage to the talus cartilage, a key component for smooth joint movement. While most sprains heal with simple care, some patients experience chronic discomfort due to focal chondral defects often missed on standard scans. ChondroFiller, a novel collagen gel treatment, offers a minimally invasive solution that promotes cartilage repair and regeneration. Clinical studies demonstrate its safety, effective integration, and potential to restore joint function. Post-treatment rehabilitation supports recovery, with many patients noticing improvements within six months. Early diagnosis and personalized care from orthopaedic specialists are crucial for optimal outcomes. ChondroFiller presents a promising alternative to traditional methods for those with persistent ankle pain seeking to regain mobility and reduce discomfort.

ChondroFiller vs Traditional Cartilage Treatments: Exploring New Options for Persistent Ankle Pain After Sprains
10 Nov 2025

ChondroFiller vs Traditional Cartilage Treatments: Exploring New Options for Persistent Ankle Pain After Sprains

Persistent ankle pain after sprains often results from cartilage damage, which traditional treatments like debridement and microfracture aim to address. Debridement removes damaged tissue but doesn't regenerate cartilage, while microfracture encourages fibrocartilage repair with variable durability. ChondroFiller introduces a novel cell-free collagen matrix scaffold that promotes more natural cartilage regeneration, showing promising clinical outcomes, particularly for small to medium defects. This less invasive approach reduces inflammation and supports healing, with patients reporting improved function and satisfaction. Optimal treatment depends on individual injury characteristics and expert medical advice, highlighting the importance of personalized care in managing ankle cartilage injuries.

How Effective Is a Single ChondroFiller Procedure for Cartilage Repair? Insights from the Latest Research
07 Nov 2025

How Effective Is a Single ChondroFiller Procedure for Cartilage Repair? Insights from the Latest Research

ChondroFiller, a collagen-based injectable treatment, offers a minimally invasive solution for cartilage injuries by promoting new cartilage growth in damaged joints. Recent studies demonstrate significant pain relief and improved joint function after just one procedure, particularly in younger patients with small cartilage defects. Unlike traditional microfracture surgery, ChondroFiller creates a supportive matrix facilitating stem cells to regenerate cartilage, supported by positive MRI findings. Personalized assessment by specialists, including clinical tests and patient history, ensures optimal outcomes and realistic expectations. Although promising, ChondroFiller is not suitable for all cartilage conditions and may require additional treatments for some. Consultation with qualified healthcare professionals is essential for tailored care and successful cartilage repair.

Preparing for and Recovering from ChondroFiller: Your Step-by-Step Guide to Successful Cartilage Repair
05 Nov 2025

Preparing for and Recovering from ChondroFiller: Your Step-by-Step Guide to Successful Cartilage Repair

ChondroFiller is an innovative collagen-based treatment for repairing small cartilage injuries, promoting natural tissue growth and joint recovery. This minimally invasive procedure acts as a scaffold inviting stem cells to regenerate healthy cartilage, reducing pain and improving mobility. Developed with expertise from Professor Paul Lee and MSK Doctors, the treatment involves careful pre-procedure preparation, including lifestyle adjustments, followed by a structured recovery plan with immobilization and physiotherapy. Clinical studies report an 80% success rate with faster healing and fewer risks compared to traditional surgeries. Patients can gradually resume low-impact activities within months and return to high-impact sports after about a year. Expert guidance ensures optimal long-term joint health, making ChondroFiller a promising solution for cartilage repair and enhanced joint function.