
Injectable, Structural Regenerative Implant for Cartilage Care
Protect • Repair • Regenerate
Cartilage injuries can turn simple movement into a challenge. Without timely treatment, damage may progress and increase the risk of arthritis or future joint replacement.
At Liquid Cartilage, our goal isjoint preservation and regeneration—not replacement. WithChondroFiller®, we deliver advanced, evidence-led care on Harley Street.

Cartilage provides the smooth, low-friction surface that lets your joints move comfortably. It doesn’t readily self-repair, but with the right scaffold and biological cues,regeneration is possible.
Act early to preserve more of what you have.

ChondroFiller® is an acellular,biologic collagen scaffold delivered in liquid form. Once placed, itgels within minutes, filling the defect and providing a framework that invites your cells to rebuild cartilage.
Think of it like “epoxy” for cartilage—without the plastic.
One treatment. One step. A chance to keep your joint for the long term.


ChondroFiller® sits in a different class—structural regenerative implant.
| Treatment | Analogy | What it Does | Limitation |
|---|---|---|---|
| HA (Hyaluronic Acid) | WD-40 | Improves lubrication for short-term comfort | Temporary; does not regenerate tissue |
| Arthrosamid® | Silicone | Acts on the synovium to reduce pain signalling | Not regenerative; literature notes complication rates up to 30% |
| ChondroFiller® | Epoxy resin | Fills defects, stabilises, and promotes true cartilage repair | Most robust injectable option for structural repair |
ChondroFiller®: our structural, regenerative approach to focal cartilage defects.
Small joints: thumb, fingers, elbow, AC joint, toes, TMJ…
From £2,100
Large joints: knee, hip, shoulder, ankle
From £2,800
Best for knee, hip, shoulder
From £6,500 (knee), £9,500 (hip/shoulder)
Our proprietary MSC Co-Delivery Technique
Introductory offer: your consultation fee is credited toward treatment if you proceed.

Quick, no-obligation chat

Comprehensive assessment with Prof. Paul Lee

Injection, Keyhole, or Liquid Cartilage™

Precise and minimally invasive



Cartilage damage won’t reverse on its own—yet with the right plan it can beprotected, repaired, and regenerated.
At Liquid Cartilage, you access world-leading science and a joint-preservation vision on Harley Street.
(Consultation fee credited towards treatment if you proceed.)
Everything you want to know about ChondroFiller® at Liquid Cartilage.
ChondroFiller® is an acellular collagen gel that fills cartilage defects and forms a scaffold for your own cells to regenerate healthy tissue. Unlike temporary injections, it supports hyaline-like restorationfor smoother motion and protection long-term.
HA or Arthrosamid® may give short-term pain relief, while ChondroFiller® aims to rebuild cartilage. Compared with replacement, it preserves your natural joint and avoids prosthesis risks. Our approach is regenerate-first.
Studies show +30 IKDC in knees,+33 Harris Hip Score in hips, and improved ankle metrics. MRI (MOCART) typically reads 70–87. Globally,>19,000 cases support safety and function.
Best for focal defects up to 6 cm² in knees, hips, ankles, or small joints. Active younger patients often benefit, but older patients may qualify if surrounding cartilage is stable.
Delivered via precise injection orkeyhole surgery. The gel sets in minutes. Expectpartial weight-bearing ~6 weeks, steady return to cycling/swimming, and most sports around~12 months alongside specialist rehab.
Harley Street location; UK ICRS Centre of Excellence. Led byProf. Paul Lee, with advanced options likeLiquid Cartilage™ (ChondroFiller® + cells) to prioritise preservation.
Discover what makes ChondroFiller® unique at Liquid Cartilage.

A focal chondral defect — localised cartilage damage in the knee — occurs independently of pain severity because cartilage carries no nerve fibres; MRI grades do not determine symptoms or treatment, which depend on depth, size, location, and clinical assessment.

Seventy to 85 per cent of patients achieve meaningful symptom relief with ChondroFiller injection at three to five years. Functional improvement averages 30 IKDC points—roughly double the clinically important threshold—but success concentrates in adults under 50 with isolated focal cartilage defects in well-aligned joints.

Microfracture and ChondroFiller injection show comparable symptom relief for the first two years, but outcomes diverge thereafter: microfracture produces fibrocartilage that degrades under joint load, while ChondroFiller provides a collagen scaffold that allows progenitor cells to deposit hyaline-like cartilage with superior load-bearing durability.

In osteochondritis dissecans, subchondral bone loses blood supply and weakens, leaving overlying cartilage vulnerable; growth plate status—not age—determines whether the condition will heal without surgery.

An ultrasound-guided collagen scaffold injected into ankle cartilage defects recruits the patient's own stem cells to regenerate tissue over 12 to 24 months, with no fixed size limit unlike surgical procedures.

ChondroFiller, an acellular collagen scaffold delivered via ultrasound-guided injection, triggers cartilage repair by signalling progenitor cells to migrate into the defect; in a 2025 wrist study, treated patients showed significantly improved cartilage quality and grip strength compared with controls.