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ChondroFiller® at the Liquid Cartilage

Injectable, Structural Regenerative Implant for Cartilage Care

Protect • Repair • Regenerate

Don’t Let Cartilage Damage Limit Your Life

Cartilage injuries can turn simple movement into a challenge. Without timely treatment, damage may progress and increase the risk of arthritis or future joint replacement.

At Liquid Cartilage, our goal isjoint preservation and regeneration—not replacement. WithChondroFiller®, we deliver advanced, evidence-led care on Harley Street.

Patient-friendly joint preservation care at Liquid Cartilage
“Repair first—keep the joint if we can.”
– Prof. Paul Lee

Why Healthy Cartilage Matters

Cartilage provides the smooth, low-friction surface that lets your joints move comfortably. It doesn’t readily self-repair, but with the right scaffold and biological cues,regeneration is possible.

Act early to preserve more of what you have.

ChondroFiller liquid scaffold visual

What Is ChondroFiller®?

ChondroFiller® is an acellular,biologic collagen scaffold delivered in liquid form. Once placed, itgels within minutes, filling the defect and providing a framework that invites your cells to rebuild cartilage.

Think of it like “epoxy” for cartilage—without the plastic.

  • Shields the damaged zone from further wear
  • Attracts native cells into a 3D scaffold
  • Supports hyaline-like regeneration (not just fibrous scar)

One treatment. One step. A chance to keep your joint for the long term.

The Evidence

Supported by a decade+ of publications and international clinical use.
Global use
>19,000
cases, no serious complications reported
Knee
+30
IKDC at 12–36 months
Hip
+33
Harris Hip Score; pain down by 6
Hand
½
pain halved; grip restored; MRI shows wider space
MRI
70–87
MOCART: consistent, high-quality repair
ChondroFiller treatment illustration 1
ChondroFiller treatment illustration 2

How Does It Compare?

ChondroFiller® sits in a different class—structural regenerative implant.

TreatmentAnalogyWhat it DoesLimitation
HA (Hyaluronic Acid)WD-40Improves lubrication for short-term comfortTemporary; does not regenerate tissue
Arthrosamid®SiliconeActs on the synovium to reduce pain signallingNot regenerative; literature notes complication rates up to 30%
ChondroFiller®Epoxy resinFills defects, stabilises, and promotes true cartilage repairMost robust injectable option for structural repair

Treatment Options at Liquid Cartilage

ChondroFiller®: our structural, regenerative approach to focal cartilage defects.

Ultrasound-Guided Precision Injections
£2,100–£2,800

Small joints: thumb, fingers, elbow, AC joint, toes, TMJ…

  • No incisions; minimal downtime
  • 1 ml of ChondroFiller
  • In-clinic procedure

From £2,100

Large joints: knee, hip, shoulder, ankle

  • In-clinic procedure
  • 2.3 ml of ChondroFiller
  • No incisions; minimal downtime

From £2,800

Keyhole Surgery (Large Joints)
£6,500–£9,500

Best for knee, hip, shoulder

  • Arthroscopic debridement
  • Direct ChondroFiller placement under vision
  • Ideal for larger/complex defects
  • ACIC (autologous collagen-induced chondrogenesis)
  • AMIC (autologous matrix-induced chondrogenesis)

From £6,500 (knee), £9,500 (hip/shoulder)

Liquid Cartilage™ (Exclusive)
£3,800–£9,500

Our proprietary MSC Co-Delivery Technique

  • Combines ChondroFiller® with MSC (medicinal signalling cells)from marrow, fat, or PRF
  • Inspired by ACI / MACI principles—delivered ina single procedure
  • Designed for larger or more complex defects
  • Best-in-class solution for cartilage loss
  • ACIC with cells
  • AMIC with cells
Injection: from £3,800 – Liquid Cartilage™
Keyhole: from £9,500 – Liquid Cartilage™

Your Journey with Us

Introductory offer: your consultation fee is credited toward treatment if you proceed.

Step 1

Discovery call

Discovery Call

Quick, no-obligation chat

Step 2

Consultation and MRI

Consultation + MRI

Comprehensive assessment with Prof. Paul Lee

Step 3

Tailored plan

Treatment Plan

Injection, Keyhole, or Liquid Cartilage™

Step 4

One-day procedure

One-Day Procedure

Precise and minimally invasive

Step 5

Rehab and follow up

Specialist Rehab & Follow-Up

Why Liquid Cartilage?

  • Prof. Paul Lee — Consultant Orthopaedic Surgeon & Honorary Professor of Sports Medicine; international leader in cartilage regeneration
  • Harley Street facilities withmotion capture and AI-supported diagnostics
  • Recognised as the UK ICRS Teaching Centre of Excellence
  • Regeneration-first philosophy: preserve joints whenever possible
Book a Discovery Call
Clinic environment
Patient recovering with guidance

Take the Next Step

Cartilage damage won’t reverse on its own—yet with the right plan it can beprotected, repaired, and regenerated.

At Liquid Cartilage, you access world-leading science and a joint-preservation vision on Harley Street.

  • Start with a Discovery Call.
  • Or book your Consultation with Prof. Lee today.

(Consultation fee credited towards treatment if you proceed.)

Verified by DoctifyVerified by Doctify

Frequently Asked Questions

Everything you want to know about ChondroFiller® at Liquid Cartilage.

What is ChondroFiller® and how does it support natural repair?

ChondroFiller® is an acellular collagen gel that fills cartilage defects and forms a scaffold for your own cells to regenerate healthy tissue. Unlike temporary injections, it supports hyaline-like restorationfor smoother motion and protection long-term.

How does it compare with other injections or joint replacement?

HA or Arthrosamid® may give short-term pain relief, while ChondroFiller® aims to rebuild cartilage. Compared with replacement, it preserves your natural joint and avoids prosthesis risks. Our approach is regenerate-first.

What outcomes have been reported?

Studies show +30 IKDC in knees,+33 Harris Hip Score in hips, and improved ankle metrics. MRI (MOCART) typically reads 70–87. Globally,>19,000 cases support safety and function.

Who is a good candidate?

Best for focal defects up to 6 cm² in knees, hips, ankles, or small joints. Active younger patients often benefit, but older patients may qualify if surrounding cartilage is stable.

What is the procedure and recovery like?

Delivered via precise injection orkeyhole surgery. The gel sets in minutes. Expectpartial weight-bearing ~6 weeks, steady return to cycling/swimming, and most sports around~12 months alongside specialist rehab.

Why choose us?

Harley Street location; UK ICRS Centre of Excellence. Led byProf. Paul Lee, with advanced options likeLiquid Cartilage™ (ChondroFiller® + cells) to prioritise preservation.

Download our Leaflet

Discover what makes ChondroFiller® unique at Liquid Cartilage.

Poster for London Cartilage Clinic featuring Professor Paul Lee, Consultant Orthopaedic Surgeon and Medical Engineer, highlighting Injectable Cartilage Regeneration with ChondroFiller®. The image explains that ChondroFiller® is a CE-marked type-I collagen gel injected directly into cartilage defects, delivered arthroscopically or fluoroscopically, and acts as a scaffold for natural cartilage regeneration. It describes clinical evidence showing improvement in knee, hip, ankle, and thumb joint conditions, and a rehabilitation pathway involving 48-hour protection, phased partial loading over 2–4 weeks, and AI-guided motion analysis for return to sport. Professor Lee is noted as Founder and Medical Director of London Cartilage Clinic on Harley Street, an international authority in regenerative surgery.Professor Paul Lee — London Cartilage Clinic expert in injectable cartilage regeneration. Promotional poster highlighting cartilage repair with ChondroFiller®: minimally invasive collagen gel injection for natural cartilage healing, faster recovery, and proven results. Suitable for knee, hip, ankle, and thumb cartilage injuries. Professor Paul Lee is an orthopaedic surgeon and PhD in Medical Engineering with 20+ years of experience in cartilage preservation. Located on Harley Street, the clinic offers AI-assisted motion tracking and world-class regenerative treatments. Private patients welcome, no GP referral required.

Latest Blog

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The Cost and Value of Knee Replacement Gel Injections
03 Feb 2026

The Cost and Value of Knee Replacement Gel Injections

Knee cartilage gel injections offer a non-surgical treatment to relieve pain and improve mobility for osteoarthritis sufferers. In the UK, costs typically range from £300 to £600 per session, with full courses costing £1,000 to £2,000. Factors affecting price include gel type, clinic location, and insurance coverage. Hyaluronic acid injections provide relief for around six months, while newer gels may last over two years. These treatments can delay more invasive surgeries like knee replacement. Expert insights emphasize patient selection and experienced administration for best outcomes. Consulting a specialist is crucial to assess suitability and cost-effectiveness, considering personal health goals and cartilage condition. While results vary, knee gel injections represent a promising, minimally invasive option for symptom improvement and cartilage support.

Week-by-Week Recovery After ChondroFiller
03 Feb 2026

Week-by-Week Recovery After ChondroFiller

Post-ChondroFiller treatment requires careful non-weight-bearing rest for up to six weeks to enable collagen gel integration and cartilage repair. Under specialist care by Professor Paul Lee and the MSK Doctors team, gradual weight-bearing and physical therapy commence between weeks three and six, enhancing joint stability and mobility. Clinical studies confirm high patient satisfaction and significant improvements, with up to 95% reaching meaningful recovery milestones. Specialist supervision ensures tailored rehabilitation, reducing risks and promoting successful outcomes. Following defined recovery phases, most patients regain full mobility within two months, safely progressing to activities like stair climbing and light jogging. Expert guidance and adherence to the recovery protocol are essential for optimal cartilage healing and long-term joint health.

Understanding Knee Gel Injections: How Modern Injectable Therapies Support Osteoarthritis Management
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Understanding Knee Gel Injections: How Modern Injectable Therapies Support Osteoarthritis Management

Knee osteoarthritis causes pain and stiffness due to cartilage wear, affecting millions in the UK. Knee gel injections, including hyaluronic acid and polyacrylamide hydrogel, offer a non-surgical treatment by replenishing joint lubrication and cushioning. Hyaluronic acid provides relief for up to six months, while synthetic hydrogels like Arthrosamid can last up to two years. Suitable for mild to moderate cases, these injections reduce symptoms, improve mobility, and may delay surgery. Administered under expert care with ultrasound guidance, they are generally safe with minimal side effects. Combining injections with rehabilitation, they form an effective part of osteoarthritis management. Always seek professional advice to determine the best treatment for your condition.

Emerging Non-Surgical Innovations in Knee Cartilage Regrowth: Exploring Modern Regenerative Therapies
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Emerging Non-Surgical Innovations in Knee Cartilage Regrowth: Exploring Modern Regenerative Therapies

Explore innovative non-surgical regenerative therapies for knee cartilage damage, including stem cell therapy, platelet-rich plasma (PRP) injections, and advanced injectable gels like ChondroFiller Liquid®. These treatments stimulate cartilage repair, reduce pain, and improve joint function by harnessing the body's natural healing processes. Ideal for early to moderate cartilage wear, they offer promising alternatives to invasive surgery, supported by expert care at specialized clinics. Learn about benefits, risks, and future trends in regenerative medicine for effective knee health management.

Decoding the Evidence: How to Understand the Clinical Data Behind ChondroFiller
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Decoding the Evidence: How to Understand the Clinical Data Behind ChondroFiller

ChondroFiller is an innovative, minimally invasive treatment for cartilage repair backed by robust clinical evidence. Studies show significant improvements in joint function and pain relief, using standardized scores like IKDC and VAS, alongside MRI imaging confirming quality cartilage regeneration. Over 19,000 global treatments report a strong safety profile with minimal adverse events. Clinical outcomes reveal high patient satisfaction and durable functional gains in knee, hand, and hip cartilage repairs. Expert interpretation by orthopaedic specialists highlights ChondroFiller's potential as a safe and effective option compared to traditional therapies. Ongoing research continues to enhance understanding of long-term benefits, supporting informed patient and clinician decisions.

ChondroFiller for Cartilage Repair: Safety and Material Insights
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ChondroFiller for Cartilage Repair: Safety and Material Insights

ChondroFiller is an innovative, minimally invasive injectable biomaterial designed for effective cartilage repair. Composed of biocompatible Type I collagen, it supports tissue regeneration and integrates seamlessly with damaged cartilage. Clinical studies demonstrate ChondroFiller's excellent safety profile, with most patients experiencing significant functional improvement and minimal side effects. Administered by expert clinicians like Professor Paul Lee at MSK Doctors, this treatment offers a reliable and patient-centered approach to managing cartilage defects. With thorough clinical validation and quality manufacturing standards, ChondroFiller presents a promising option for enhancing joint function and recovery without major surgery.