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ChondroFiller® at the Liquid Cartilage

Injectable, Structural Regenerative Implant for Cartilage Care

Protect • Repair • Regenerate

Don’t Let Cartilage Damage Limit Your Life

Cartilage injuries can turn simple movement into a challenge. Without timely treatment, damage may progress and increase the risk of arthritis or future joint replacement.

At Liquid Cartilage, our goal isjoint preservation and regeneration—not replacement. WithChondroFiller®, we deliver advanced, evidence-led care on Harley Street.

Patient-friendly joint preservation care at Liquid Cartilage
“Repair first—keep the joint if we can.”
– Prof. Paul Lee

Why Healthy Cartilage Matters

Cartilage provides the smooth, low-friction surface that lets your joints move comfortably. It doesn’t readily self-repair, but with the right scaffold and biological cues,regeneration is possible.

Act early to preserve more of what you have.

ChondroFiller liquid scaffold visual

What Is ChondroFiller®?

ChondroFiller® is an acellular,biologic collagen scaffold delivered in liquid form. Once placed, itgels within minutes, filling the defect and providing a framework that invites your cells to rebuild cartilage.

Think of it like “epoxy” for cartilage—without the plastic.

  • Shields the damaged zone from further wear
  • Attracts native cells into a 3D scaffold
  • Supports hyaline-like regeneration (not just fibrous scar)

One treatment. One step. A chance to keep your joint for the long term.

The Evidence

Supported by a decade+ of publications and international clinical use.
Global use
>19,000
cases, no serious complications reported
Knee
+30
IKDC at 12–36 months
Hip
+33
Harris Hip Score; pain down by 6
Hand
½
pain halved; grip restored; MRI shows wider space
MRI
70–87
MOCART: consistent, high-quality repair
ChondroFiller treatment illustration 1
ChondroFiller treatment illustration 2

How Does It Compare?

ChondroFiller® sits in a different class—structural regenerative implant.

TreatmentAnalogyWhat it DoesLimitation
HA (Hyaluronic Acid)WD-40Improves lubrication for short-term comfortTemporary; does not regenerate tissue
Arthrosamid®SiliconeActs on the synovium to reduce pain signallingNot regenerative; literature notes complication rates up to 30%
ChondroFiller®Epoxy resinFills defects, stabilises, and promotes true cartilage repairMost robust injectable option for structural repair

Treatment Options at Liquid Cartilage

ChondroFiller®: our structural, regenerative approach to focal cartilage defects.

Ultrasound-Guided Precision Injections
£2,100–£2,800

Small joints: thumb, fingers, elbow, AC joint, toes, TMJ…

  • No incisions; minimal downtime
  • 1 ml of ChondroFiller
  • In-clinic procedure

From £2,100

Large joints: knee, hip, shoulder, ankle

  • In-clinic procedure
  • 2.3 ml of ChondroFiller
  • No incisions; minimal downtime

From £2,800

Keyhole Surgery (Large Joints)
£6,500–£9,500

Best for knee, hip, shoulder

  • Arthroscopic debridement
  • Direct ChondroFiller placement under vision
  • Ideal for larger/complex defects
  • ACIC (autologous collagen-induced chondrogenesis)
  • AMIC (autologous matrix-induced chondrogenesis)

From £6,500 (knee), £9,500 (hip/shoulder)

Liquid Cartilage™ (Exclusive)
£3,800–£9,500

Our proprietary MSC Co-Delivery Technique

  • Combines ChondroFiller® with MSC (medicinal signalling cells)from marrow, fat, or PRF
  • Inspired by ACI / MACI principles—delivered ina single procedure
  • Designed for larger or more complex defects
  • Best-in-class solution for cartilage loss
  • ACIC with cells
  • AMIC with cells
Injection: from £3,800 – Liquid Cartilage™
Keyhole: from £9,500 – Liquid Cartilage™

Your Journey with Us

Introductory offer: your consultation fee is credited toward treatment if you proceed.

Step 1

Discovery call

Discovery Call

Quick, no-obligation chat

Step 2

Consultation and MRI

Consultation + MRI

Comprehensive assessment with Prof. Paul Lee

Step 3

Tailored plan

Treatment Plan

Injection, Keyhole, or Liquid Cartilage™

Step 4

One-day procedure

One-Day Procedure

Precise and minimally invasive

Step 5

Rehab and follow up

Specialist Rehab & Follow-Up

Why Liquid Cartilage?

  • Prof. Paul Lee— Consultant Orthopaedic Surgeon & Honorary Professor of Sports Medicine; international leader in cartilage regeneration
  • Harley Street facilities withmotion capture and AI-supported diagnostics
  • Recognised as the UK ICRS Teaching Centre of Excellence
  • Regeneration-first philosophy: preserve joints whenever possible
Book a Discovery Call
Clinic environment
Patient recovering with guidance

Take the Next Step

Cartilage damage won’t reverse on its own—yet with the right plan it can beprotected, repaired, and regenerated.

At Liquid Cartilage, you access world-leading science and a joint-preservation vision on Harley Street.

  • Start with a Discovery Call.
  • Or book your Consultation with Prof. Lee today.

(Consultation fee credited towards treatment if you proceed.)

Verified by DoctifyVerified by Doctify

Frequently Asked Questions

Everything you want to know about ChondroFiller® at Liquid Cartilage.

What is ChondroFiller® and how does it support natural repair?

ChondroFiller® is an acellular collagen gel that fills cartilage defects and forms a scaffold for your own cells to regenerate healthy tissue. Unlike temporary injections, it supports hyaline-like restorationfor smoother motion and protection long-term.

How does it compare with other injections or joint replacement?

HA or Arthrosamid® may give short-term pain relief, while ChondroFiller® aims to rebuild cartilage. Compared with replacement, it preserves your natural joint and avoids prosthesis risks. Our approach is regenerate-first.

What outcomes have been reported?

Studies show +30 IKDC in knees,+33 Harris Hip Score in hips, and improved ankle metrics. MRI (MOCART) typically reads 70–87. Globally,>19,000 cases support safety and function.

Who is a good candidate?

Best for focal defects up to 6 cm² in knees, hips, ankles, or small joints. Active younger patients often benefit, but older patients may qualify if surrounding cartilage is stable.

What is the procedure and recovery like?

Delivered via precise injection orkeyhole surgery. The gel sets in minutes. Expectpartial weight-bearing ~6 weeks, steady return to cycling/swimming, and most sports around~12 months alongside specialist rehab.

Why choose us?

Harley Street location; UK ICRS Centre of Excellence. Led byProf. Paul Lee, with advanced options likeLiquid Cartilage™ (ChondroFiller® + cells) to prioritise preservation.

Download our Leaflet

Discover what makes ChondroFiller® unique at Liquid Cartilage.

Poster for London Cartilage Clinic featuring Professor Paul Lee, Consultant Orthopaedic Surgeon and Medical Engineer, highlighting Injectable Cartilage Regeneration with ChondroFiller®. The image explains that ChondroFiller® is a CE-marked type-I collagen gel injected directly into cartilage defects, delivered arthroscopically or fluoroscopically, and acts as a scaffold for natural cartilage regeneration. It describes clinical evidence showing improvement in knee, hip, ankle, and thumb joint conditions, and a rehabilitation pathway involving 48-hour protection, phased partial loading over 2–4 weeks, and AI-guided motion analysis for return to sport. Professor Lee is noted as Founder and Medical Director of London Cartilage Clinic on Harley Street, an international authority in regenerative surgery.Professor Paul Lee — London Cartilage Clinic expert in injectable cartilage regeneration. Promotional poster highlighting cartilage repair with ChondroFiller®: minimally invasive collagen gel injection for natural cartilage healing, faster recovery, and proven results. Suitable for knee, hip, ankle, and thumb cartilage injuries. Professor Paul Lee is an orthopaedic surgeon and PhD in Medical Engineering with 20+ years of experience in cartilage preservation. Located on Harley Street, the clinic offers AI-assisted motion tracking and world-class regenerative treatments. Private patients welcome, no GP referral required.

Latest Blog

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When early joint pain needs cartilage review
27 May 2026

When early joint pain needs cartilage review

Persistent joint pain with everyday tasks, stiffness, catching, or loss of strength after a sprain, fracture, or repeated throwing needs specialist review, because early cartilage damage still leaves room for joint-preserving treatment. In ankle, thumb base and throwing-elbow disease, stage and stability determine whether repair remains possible before end-stage collapse.

When bracing osteotomy and chondroplasty make sense
27 May 2026

When bracing osteotomy and chondroplasty make sense

Unloader bracing can reduce pain in unicompartmental knee osteoarthritis for up to 52 weeks, but it only shifts load. High tibial or distal femoral osteotomy changes alignment when varus or valgus malalignment drives overload, while chondroplasty merely trims unstable cartilage flaps to ease catching.

Is Liquid Cartilage right for hip or ankle defects
27 May 2026

Is Liquid Cartilage right for hip or ankle defects

Liquid Cartilage™, meaning ChondroFiller™, is an arthroscopic collagen matrix used for localised hip or ankle cartilage defects, not diffuse osteoarthritis. In a small 2021 hip cohort, 17 of 21 patients available at 3 to 5 years had good or excellent results, but ankle evidence remains thinner than for microfracture.

Which cartilage repair option fits your defect
26 May 2026

Which cartilage repair option fits your defect

Cartilage repair choice is driven first by defect size, joint and damage pattern: smaller isolated lesions tend towards OATS or scaffold-based repair, while larger symptomatic defects more often need AMIC, MACI or OCA. In the knee, MACI outperformed microfracture at 2 and 5 years for larger defects.

How long is the preservation window in knee OCD
26 May 2026

How long is the preservation window in knee OCD

Knee OCD has no single countdown clock; the preservation window is the stable-lesion stage before instability or detachment, with MRI and clinical assessment driving decisions. In children with open growth plates, stable lesions are often given a 3- to 6-month joint-preserving trial because healing remains plausible.

When Liquid Cartilage may be considered
24 May 2026

When Liquid Cartilage may be considered

Liquid Cartilage™ is considered for a defined symptomatic cartilage defect treated arthroscopically, not for diffuse joint wear: ChondroFiller™ is a cell-free type I collagen scaffold placed into the defect and sets into a hydrogel in about 3–5 minutes.

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