ChondroFiller® at the Liquid Cartilage
Injectable, Structural Regenerative Implant for Cartilage Care
Protect • Repair • Regenerate
Don’t Let Cartilage Damage Limit Your Life
Cartilage injuries can turn simple movement into a challenge. Without timely treatment, damage may progress and increase the risk of arthritis or future joint replacement.
At Liquid Cartilage, our goal isjoint preservation and regeneration—not replacement. WithChondroFiller®, we deliver advanced, evidence-led care on Harley Street.
Why Healthy Cartilage Matters
Cartilage provides the smooth, low-friction surface that lets your joints move comfortably. It doesn’t readily self-repair, but with the right scaffold and biological cues,regeneration is possible.
Act early to preserve more of what you have.
What Is ChondroFiller®?
ChondroFiller® is an acellular,biologic collagen scaffold delivered in liquid form. Once placed, itgels within minutes, filling the defect and providing a framework that invites your cells to rebuild cartilage.
Think of it like “epoxy” for cartilage—without the plastic.
- Shields the damaged zone from further wear
- Attracts native cells into a 3D scaffold
- Supports hyaline-like regeneration (not just fibrous scar)
One treatment. One step. A chance to keep your joint for the long term.
The Evidence
How Does It Compare?
ChondroFiller® sits in a different class—structural regenerative implant.
| Treatment | Analogy | What it Does | Limitation |
|---|---|---|---|
| HA (Hyaluronic Acid) | WD-40 | Improves lubrication for short-term comfort | Temporary; does not regenerate tissue |
| Arthrosamid® | Silicone | Acts on the synovium to reduce pain signalling | Not regenerative; literature notes complication rates up to 30% |
| ChondroFiller® | Epoxy resin | Fills defects, stabilises, and promotes true cartilage repair | Most robust injectable option for structural repair |
Treatment Options at Liquid Cartilage
ChondroFiller®: our structural, regenerative approach to focal cartilage defects.
Small joints: thumb, fingers, elbow, AC joint, toes, TMJ…
- No incisions; minimal downtime
- 1 ml of ChondroFiller
- In-clinic procedure
From £2,100
Large joints: knee, hip, shoulder, ankle
- In-clinic procedure
- 2.3 ml of ChondroFiller
- No incisions; minimal downtime
From £2,800
Best for knee, hip, shoulder
- Arthroscopic debridement
- Direct ChondroFiller placement under vision
- Ideal for larger/complex defects
- ACIC (autologous collagen-induced chondrogenesis)
- AMIC (autologous matrix-induced chondrogenesis)
From £6,500 (knee), £9,500 (hip/shoulder)
Our proprietary MSC Co-Delivery Technique
- Combines ChondroFiller® with MSC (medicinal signalling cells)from marrow, fat, or PRF
- Inspired by ACI / MACI principles—delivered ina single procedure
- Designed for larger or more complex defects
- Best-in-class solution for cartilage loss
- ACIC with cells
- AMIC with cells
Keyhole: from £9,500 – Liquid Cartilage™
Your Journey with Us
Introductory offer: your consultation fee is credited toward treatment if you proceed.
Step 1
Discovery Call
Quick, no-obligation chat
Step 2
Consultation + MRI
Comprehensive assessment with Prof. Paul Lee
Step 3
Treatment Plan
Injection, Keyhole, or Liquid Cartilage™
Step 4
One-Day Procedure
Precise and minimally invasive
Step 5
Specialist Rehab & Follow-Up
Why Liquid Cartilage?
- Prof. Paul Lee— Consultant Orthopaedic Surgeon & Honorary Professor of Sports Medicine; international leader in cartilage regeneration
- Harley Street facilities withmotion capture and AI-supported diagnostics
- Recognised as the UK ICRS Teaching Centre of Excellence
- Regeneration-first philosophy: preserve joints whenever possible
Take the Next Step
Cartilage damage won’t reverse on its own—yet with the right plan it can beprotected, repaired, and regenerated.
At Liquid Cartilage, you access world-leading science and a joint-preservation vision on Harley Street.
- Start with a Discovery Call.
- Or book your Consultation with Prof. Lee today.
(Consultation fee credited towards treatment if you proceed.)
Frequently Asked Questions
Everything you want to know about ChondroFiller® at Liquid Cartilage.
What is ChondroFiller® and how does it support natural repair?
ChondroFiller® is an acellular collagen gel that fills cartilage defects and forms a scaffold for your own cells to regenerate healthy tissue. Unlike temporary injections, it supports hyaline-like restorationfor smoother motion and protection long-term.
How does it compare with other injections or joint replacement?
HA or Arthrosamid® may give short-term pain relief, while ChondroFiller® aims to rebuild cartilage. Compared with replacement, it preserves your natural joint and avoids prosthesis risks. Our approach is regenerate-first.
What outcomes have been reported?
Studies show +30 IKDC in knees,+33 Harris Hip Score in hips, and improved ankle metrics. MRI (MOCART) typically reads 70–87. Globally,>19,000 cases support safety and function.
Who is a good candidate?
Best for focal defects up to 6 cm² in knees, hips, ankles, or small joints. Active younger patients often benefit, but older patients may qualify if surrounding cartilage is stable.
What is the procedure and recovery like?
Delivered via precise injection orkeyhole surgery. The gel sets in minutes. Expectpartial weight-bearing ~6 weeks, steady return to cycling/swimming, and most sports around~12 months alongside specialist rehab.
Why choose us?
Harley Street location; UK ICRS Centre of Excellence. Led byProf. Paul Lee, with advanced options likeLiquid Cartilage™ (ChondroFiller® + cells) to prioritise preservation.
Download our Leaflet
Discover what makes ChondroFiller® unique at Liquid Cartilage.
Latest Blog
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Knee OCD staging and when surgery is needed
Whether knee osteochondritis dissecans requires surgery or heals with conservative care depends chiefly on skeletal maturity: stable juvenile lesions achieve healing in roughly 52–67% of cases, whilst spontaneous healing is uncommon in adults and surgery is typically necessary.
ChondroFiller injection vs ACI and MACI
ChondroFiller injection and ACI/MACI produce comparable functional improvement for focal cartilage defects, but reoperation rates diverge sharply—3–8% versus up to 37%—a gap unresolved by head-to-head clinical comparison.
Is the patella suitable for ChondroFiller injection?
ChondroFiller injection, an acellular collagen scaffold, gels at patellar cartilage defects and recruits the patient's own progenitor cells to repair the tissue—without penetrating bone or producing the fibrocartilage that microfracture generates and that deteriorates within two to three years.
ChondroFiller injection for ankle cartilage damage
Focal cartilage damage on the talar dome — lesions no larger than 1.2 cm² with defined borders — is treated with ChondroFiller, a Type I collagen scaffold that polymerises in an outpatient clinic and recruits the ankle's own repair cells.
OATS versus Microfracture at Ten Years in Athletes
Competitive athletes undergoing OATS showed 14% failure at ten years versus 38% for microfracture—a gap appearing between years five and ten as fibrocartilage repair tissue progressively degrades under athletic loading.
How lesion size shapes knee cartilage treatment after MRI
Lesion area in square centimetres, not depth grade, is the single most influential variable determining knee cartilage treatment: under 2 cm² conservative care, 2–4 cm² mixed surgical options, over 4 cm² structural grafting.