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ChondroFiller® at the Liquid Cartilage

Injectable, Structural Regenerative Implant for Cartilage Care

Protect • Repair • Regenerate

Don’t Let Cartilage Damage Limit Your Life

Cartilage injuries can turn simple movement into a challenge. Without timely treatment, damage may progress and increase the risk of arthritis or future joint replacement.

At Liquid Cartilage, our goal isjoint preservation and regeneration—not replacement. WithChondroFiller®, we deliver advanced, evidence-led care on Harley Street.

Patient-friendly joint preservation care at Liquid Cartilage
“Repair first—keep the joint if we can.”
– Prof. Paul Lee

Why Healthy Cartilage Matters

Cartilage provides the smooth, low-friction surface that lets your joints move comfortably. It doesn’t readily self-repair, but with the right scaffold and biological cues,regeneration is possible.

Act early to preserve more of what you have.

ChondroFiller liquid scaffold visual

What Is ChondroFiller®?

ChondroFiller® is an acellular,biologic collagen scaffold delivered in liquid form. Once placed, itgels within minutes, filling the defect and providing a framework that invites your cells to rebuild cartilage.

Think of it like “epoxy” for cartilage—without the plastic.

  • Shields the damaged zone from further wear
  • Attracts native cells into a 3D scaffold
  • Supports hyaline-like regeneration (not just fibrous scar)

One treatment. One step. A chance to keep your joint for the long term.

The Evidence

Supported by a decade+ of publications and international clinical use.
Global use
>19,000
cases, no serious complications reported
Knee
+30
IKDC at 12–36 months
Hip
+33
Harris Hip Score; pain down by 6
Hand
½
pain halved; grip restored; MRI shows wider space
MRI
70–87
MOCART: consistent, high-quality repair
ChondroFiller treatment illustration 1
ChondroFiller treatment illustration 2

How Does It Compare?

ChondroFiller® sits in a different class—structural regenerative implant.

TreatmentAnalogyWhat it DoesLimitation
HA (Hyaluronic Acid)WD-40Improves lubrication for short-term comfortTemporary; does not regenerate tissue
Arthrosamid®SiliconeActs on the synovium to reduce pain signallingNot regenerative; literature notes complication rates up to 30%
ChondroFiller®Epoxy resinFills defects, stabilises, and promotes true cartilage repairMost robust injectable option for structural repair

Treatment Options at Liquid Cartilage

ChondroFiller®: our structural, regenerative approach to focal cartilage defects.

Ultrasound-Guided Precision Injections
£2,100–£2,800

Small joints: thumb, fingers, elbow, AC joint, toes, TMJ…

  • No incisions; minimal downtime
  • 1 ml of ChondroFiller
  • In-clinic procedure

From £2,100

Large joints: knee, hip, shoulder, ankle

  • In-clinic procedure
  • 2.3 ml of ChondroFiller
  • No incisions; minimal downtime

From £2,800

Keyhole Surgery (Large Joints)
£6,500–£9,500

Best for knee, hip, shoulder

  • Arthroscopic debridement
  • Direct ChondroFiller placement under vision
  • Ideal for larger/complex defects
  • ACIC (autologous collagen-induced chondrogenesis)
  • AMIC (autologous matrix-induced chondrogenesis)

From £6,500 (knee), £9,500 (hip/shoulder)

Liquid Cartilage™ (Exclusive)
£3,800–£9,500

Our proprietary MSC Co-Delivery Technique

  • Combines ChondroFiller® with MSC (medicinal signalling cells)from marrow, fat, or PRF
  • Inspired by ACI / MACI principles—delivered ina single procedure
  • Designed for larger or more complex defects
  • Best-in-class solution for cartilage loss
  • ACIC with cells
  • AMIC with cells
Injection: from £3,800 – Liquid Cartilage™
Keyhole: from £9,500 – Liquid Cartilage™

Your Journey with Us

Introductory offer: your consultation fee is credited toward treatment if you proceed.

Step 1

Discovery call

Discovery Call

Quick, no-obligation chat

Step 2

Consultation and MRI

Consultation + MRI

Comprehensive assessment with Prof. Paul Lee

Step 3

Tailored plan

Treatment Plan

Injection, Keyhole, or Liquid Cartilage™

Step 4

One-day procedure

One-Day Procedure

Precise and minimally invasive

Step 5

Rehab and follow up

Specialist Rehab & Follow-Up

Why Liquid Cartilage?

  • Prof. Paul Lee — Consultant Orthopaedic Surgeon & Honorary Professor of Sports Medicine; international leader in cartilage regeneration
  • Harley Street facilities withmotion capture and AI-supported diagnostics
  • Recognised as the UK ICRS Teaching Centre of Excellence
  • Regeneration-first philosophy: preserve joints whenever possible
Book a Discovery Call
Clinic environment
Patient recovering with guidance

Take the Next Step

Cartilage damage won’t reverse on its own—yet with the right plan it can beprotected, repaired, and regenerated.

At Liquid Cartilage, you access world-leading science and a joint-preservation vision on Harley Street.

  • Start with a Discovery Call.
  • Or book your Consultation with Prof. Lee today.

(Consultation fee credited towards treatment if you proceed.)

Verified by DoctifyVerified by Doctify

Frequently Asked Questions

Everything you want to know about ChondroFiller® at Liquid Cartilage.

What is ChondroFiller® and how does it support natural repair?

ChondroFiller® is an acellular collagen gel that fills cartilage defects and forms a scaffold for your own cells to regenerate healthy tissue. Unlike temporary injections, it supports hyaline-like restorationfor smoother motion and protection long-term.

How does it compare with other injections or joint replacement?

HA or Arthrosamid® may give short-term pain relief, while ChondroFiller® aims to rebuild cartilage. Compared with replacement, it preserves your natural joint and avoids prosthesis risks. Our approach is regenerate-first.

What outcomes have been reported?

Studies show +30 IKDC in knees,+33 Harris Hip Score in hips, and improved ankle metrics. MRI (MOCART) typically reads 70–87. Globally,>19,000 cases support safety and function.

Who is a good candidate?

Best for focal defects up to 6 cm² in knees, hips, ankles, or small joints. Active younger patients often benefit, but older patients may qualify if surrounding cartilage is stable.

What is the procedure and recovery like?

Delivered via precise injection orkeyhole surgery. The gel sets in minutes. Expectpartial weight-bearing ~6 weeks, steady return to cycling/swimming, and most sports around~12 months alongside specialist rehab.

Why choose us?

Harley Street location; UK ICRS Centre of Excellence. Led byProf. Paul Lee, with advanced options likeLiquid Cartilage™ (ChondroFiller® + cells) to prioritise preservation.

Download our Leaflet

Discover what makes ChondroFiller® unique at Liquid Cartilage.

Poster for London Cartilage Clinic featuring Professor Paul Lee, Consultant Orthopaedic Surgeon and Medical Engineer, highlighting Injectable Cartilage Regeneration with ChondroFiller®. The image explains that ChondroFiller® is a CE-marked type-I collagen gel injected directly into cartilage defects, delivered arthroscopically or fluoroscopically, and acts as a scaffold for natural cartilage regeneration. It describes clinical evidence showing improvement in knee, hip, ankle, and thumb joint conditions, and a rehabilitation pathway involving 48-hour protection, phased partial loading over 2–4 weeks, and AI-guided motion analysis for return to sport. Professor Lee is noted as Founder and Medical Director of London Cartilage Clinic on Harley Street, an international authority in regenerative surgery.Professor Paul Lee — London Cartilage Clinic expert in injectable cartilage regeneration. Promotional poster highlighting cartilage repair with ChondroFiller®: minimally invasive collagen gel injection for natural cartilage healing, faster recovery, and proven results. Suitable for knee, hip, ankle, and thumb cartilage injuries. Professor Paul Lee is an orthopaedic surgeon and PhD in Medical Engineering with 20+ years of experience in cartilage preservation. Located on Harley Street, the clinic offers AI-assisted motion tracking and world-class regenerative treatments. Private patients welcome, no GP referral required.

Latest Blog

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How ChondroFiller is Transforming the Treatment of Knee Pain and Cartilage Damage: What Patients Should Know
28 Nov 2025

How ChondroFiller is Transforming the Treatment of Knee Pain and Cartilage Damage: What Patients Should Know

Knee pain and cartilage damage significantly impact daily life, often causing discomfort and limited mobility. Traditional treatments like surgery and injections may not always be effective or minimally invasive. ChondroFiller presents a novel, microinvasive gel injection therapy that promotes natural cartilage repair, offering faster recovery and reduced discomfort. Supported by studies demonstrating high success rates and improved joint function, this approach targets local cartilage defects precisely. Expert assessment by specialists, such as Professor Paul Lee and his team, ensures personalized care for optimal outcomes. If you experience knee pain or suspect cartilage issues, professional consultation is essential to explore whether ChondroFiller can provide a safe, effective solution for your joint health.

Why Preserving Joint Health Requires ChondroFiller: Exploring the Science Behind Modern Cartilage Repair
26 Nov 2025

Why Preserving Joint Health Requires ChondroFiller: Exploring the Science Behind Modern Cartilage Repair

ChondroFiller offers a promising biological treatment for cartilage damage, a condition notoriously difficult to heal due to cartilage's lack of blood supply. By using an acellular collagen matrix, ChondroFiller acts as a scaffold encouraging cartilage regeneration and joint repair. Clinical studies show high patient satisfaction and significant improvements in pain and mobility, enabling many to resume active lifestyles. Ideal for individuals with early to moderate cartilage wear or injury, this treatment represents an innovative advancement beyond traditional symptom management. Expert care from specialists like Professor Paul Lee and MSK Doctors ensures personalized treatment and optimal recovery. Exploring ChondroFiller could be key to restoring joint health and improving quality of life for those suffering from cartilage-related joint pain.

ChondroFiller Versus Hyaluronic Acid Injections: Understanding the Differences in Joint Cartilage Treatments
24 Nov 2025

ChondroFiller Versus Hyaluronic Acid Injections: Understanding the Differences in Joint Cartilage Treatments

Explore the differences between ChondroFiller and hyaluronic acid injections for joint cartilage damage. ChondroFiller promotes cartilage repair and regeneration through a minimally invasive procedure, offering long-term healing. In contrast, hyaluronic acid injections provide temporary relief by lubricating joints and reducing pain. Insights from Professor Paul Lee and MSK Doctors highlight personalized treatment options tailored to patient needs, aiding informed decisions for managing cartilage injuries. Understand the benefits and uses of each treatment to improve joint function and quality of life.

Is the ChondroFiller Procedure Really Complex? Demystifying Modern Cartilage Repair
21 Nov 2025

Is the ChondroFiller Procedure Really Complex? Demystifying Modern Cartilage Repair

The ChondroFiller procedure offers a minimally invasive, efficient solution for cartilage repair using a collagen-based liquid implant applied through precise arthroscopic keyhole surgery. This innovative, cell-free technique preserves existing cartilage and promotes natural healing, resulting in reduced trauma, faster recovery, and significant improvements in joint function. While generally less complex than traditional surgeries, successful outcomes depend on surgical expertise, especially for challenging joints like the hip. Clinics with skilled teams specializing in cartilage repair, such as MSK Doctors, ensure precise application and optimal patient results. Recognized in recent studies for its safety and effectiveness, ChondroFiller represents a patient-friendly advancement in treating cartilage damage and restoring mobility.

ChondroFiller Explained: How Cell-Free, Injectable Solutions Are Transforming Cartilage Repair
19 Nov 2025

ChondroFiller Explained: How Cell-Free, Injectable Solutions Are Transforming Cartilage Repair

ChondroFiller is an innovative, cell-free injectable gel designed to repair cartilage damage with minimal invasiveness, offering a safer alternative to traditional surgery. By providing a supportive scaffold, it promotes natural healing of cartilage, especially in challenging joints like the hip. The treatment involves a single-step arthroscopic procedure with precise injection, leading to reduced pain and quicker recovery times. While highly effective for specific cartilage defects, it is best administered under expert guidance to ensure suitability and optimal outcomes. Clinics such as MSK Doctors provide comprehensive assessments and personalised care, making ChondroFiller a promising option in regenerative joint medicine.

ChondroFiller: Revolutionising Cartilage Healing with a Minimally Invasive, Cell-Free Approach
17 Nov 2025

ChondroFiller: Revolutionising Cartilage Healing with a Minimally Invasive, Cell-Free Approach

ChondroFiller presents a novel, minimally invasive treatment for cartilage injuries, using a cell-free type I collagen gel to promote natural repair in damaged joints. Unlike traditional multi-step surgeries, this one-step arthroscopic procedure delivers the gel precisely via malleable needles, reducing recovery time and patient discomfort. Expert assessment by MSK Doctors ensures personalized care, optimizing outcomes for those suffering from full-thickness chondral defects. This innovative approach offers hope for improved joint function and faster healing, marking a significant advancement in orthopedic cartilage repair.